In San Francisco, Jill Valentine is cover with a zombi eruption and a new T-Virus, Leon Jack Kennedy is on the trail of a kidnap Defense Advanced Research Projects Agency scientist, and Claire Redfield is investigate a monstrous fish that is kill giant in the bay. join by Chris Redfield and Rebekah William Chambers, they detect the trail of hint from their separate case all meet on the same location, Alcatraz Island, where a new immorality has take abode and expect their reaching.